Hey @thisisbbc, I think you can only set a custom data directory on the initial installation, not through the configuration file or after the wallet is installed. During installation, the first popup option is to install the Qtum Core binaries (executable programs) in a custom location: Qtum Core Location Later in the process with another popup you can pick a custom location for the Qtum data directory, here a new folder named "Data" in the "F:\Qtum" directory: Qtum data directory If you have already installet Qtum Core (carefully save your wallet.dat file if you have started using the wallet!), just uninstall, delete all the Qtum files, do a reinstallation and select the custom directory locations.